Massive single-cell atlas across human tissues highlights cell types where disease genes are active
Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need to know where they are active in the body. Resear.....»»
All Teddy Bear locations in Fallout 76
You will never need a teddy bear more than after the bombs drop in Fallout 76. This game has 12 different types of stuffed animal hidden in various locations......»»
Loved Fallout on Amazon Prime? Get Fallout 4 for PC for only $8
With the Fallout TV show being such a massive hit, now is the perfect time to revisit or play Fallout 4, and this deal will get you a copy for just $8......»»
AI tool recognizes serious ocular disease in horses
Colloquially known as moon blindness, equine recurrent uveitis (ERU) is an inflammatory ocular disease in horses, which can lead to blindness or loss of the affected eye. It is one of the most common eye diseases in horses and has a major economic im.....»»
Pushing the limits of sub-kilowatt electric propulsion technology for space mission concepts
NASA has developed an advanced propulsion technology to facilitate future planetary exploration missions using small spacecraft. Not only will this technology enable new types of planetary science missions, one of NASA's commercial partners is alread.....»»
Africa"s megacities threatened by heat, floods, disease—action needed to start greening, adapt to climate change
Cities cover just 3% of the planet. But they emit 78% of all global greenhouse gas emissions, absorb 80% of final global energy (what consumers use) and consume 60% of clean drinking water......»»
Will the US ban the use of single-use plastics like England, India, Hong Kong and other countries?
Madhavi Venkatesan, associate teaching professor of economics at Northeastern University, is convinced that human convenience is an expense the environment cannot afford......»»
Ultrasensitive photonic crystal detects single particles down to 50 nanometers
Using an ultrasensitive photonic crystal, TU/e researchers were able to detect single particles down to 50 nanometers in diameter. The new research has just been published in the journal Optica......»»
How studying trends in human lifespans can measure progress in addressing inequality
People are living longer lives compared to previous generations but, over the last few decades, there has been a hidden shift—they are passing away at increasingly similar ages......»»
Can climate change accelerate transmission of malaria? New research sheds light on impacts of temperature
Malaria is a mosquito-borne disease caused by a parasite that spreads from bites of infected female Anopheles mosquitoes. If left untreated in humans, malaria can cause severe symptoms, health complications and even death......»»
No laughing matter, unfortunately: Why aggressive humor might pay for CEOs
Humor is central to human interaction and social perception. However, hardly any research has looked at how humor works in top management communication. This is where a new conceptual study comes in. Titled "Good Fun or Laughingstock? How CEO Humor A.....»»
Imaging technique shows new details of peptide structures
A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies—stacks of peptides that include amyloid beta, most notably associated with Alzheimer's disease......»»
Updating California’s grid for EVs may cost up to $20 billion
Charging electric vehicles at home will exceed most power lines' capacity. Enlarge (credit: boonchai wedmakawand) California's electric grid, with its massive solar production and booming battery installations, is alread.....»»
Meet Me At Open Hardware Summit 2024 Montreal
Last year’s Open Hardware Summit was one of the absolute highlights of my year. It was among the nerdiest, most inclusive, most stimulating events I’ve ever had the pleasure of attending. If my endorsement alone is enough to persuade you that yo.....»»
Black hole "traffic jams" discovered in galactic centers by astronomers
An international study, led by researchers from Monash University, has revealed crucial insights into black hole dynamics within massive disks at the centers of galaxies......»»
Researchers unveil PI3K enzyme"s dual accelerator and brake mechanisms
A group of researchers have expanded conventional knowledge on a critical enzyme that controls cell migration. In a publication in the journal Nature Communications, they reported that phosphoinositide 3-kinase (PI3K) not only acts as an accelerator.....»»
Unveiling the mysteries of cell division in embryos with timelapse photography
The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis are well-studied in the so-called somatic cells—the cells that have a specialized function, like skin and muscle cells—they remain elusive in the first cells of.....»»
AI designs active pharmaceutical ingredients quickly and easily based on protein structures
A new computer process developed by chemists at ETH Zurich makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process, detailed in Nature Communications, could re.....»»
Climate change supercharged a heat dome, intensifying 2021 fire season, study finds
As a massive heat dome lingered over the Pacific Northwest three years ago, swaths of North America simmered—and then burned. Wildfires charred more than 18.5 million acres across the continent, with the most land burned in Canada and California......»»
Giant virus discovered in wastewater treatment plant infects deadly parasite
The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an intern.....»»
Enhanced CRISPR method enables stable insertion of large genes into the DNA of higher plants
Scientists at the Leibniz Institute of Plant Biochemistry (IPB) have succeeded for the first time in stably and precisely inserting large gene segments into the DNA of higher plants very efficiently. To do this, they optimized the gene-editing method.....»»