Mass spectrometry uncovers actions of protein "glues"
A screening technique commonly used in drug discovery can yield important details about the actions of molecular 'glues' in protein interactions......»»
New biosensor illuminates physiological signals in living animals
Eric Schreiter and Luke Lavis thought they had figured it out. In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Independent origins of frog glue and its role in predator evasion
Skin-secreted adhesives, or glues, are highly effective defense adaptations that have evolved recurrently in a small number of amphibians. From an ecological standpoint, this rapidly solidifying material—essentially, a sticky slime—encumbers the.....»»
Ultra-Precise Particle Measurement Narrows Pathway to ‘New Physics’
A long-awaited calculation of the W boson’s mass agrees with theory, contradicting a previous anomaly that had raised the possibility of new physics beyond the Standard Model.....»»
MS Coast mother blames police for son’s death in restaurant mass shooting, lawsuit says
MS Coast mother blames police for son’s death in restaurant mass shooting, lawsuit says.....»»
VW dealers get glimpse of future U.S. product
VW's U.S. sales rose 26 percent in the first half of 2024, the largest gain of any mass-market brand. VW dealers to get fresh products by year-end......»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
Reducing floodplain development doesn"t need to be complex, say researchers
A paper, titled "How local governments avoid floodplain development through consistent implementation of routine municipal ordinances, plans, and programs," published in Oxford Open Climate Change uncovers evidence suggesting that, contrary to expect.....»»
Mass. dealership lawsuit against Nissan can proceed, federal judge rules
A Massachusetts dealership can pursue claims that Nissan North America's sales performance metrics and use of volume-based sales incentive programs were arbitrary and unfair, a federal judge ruled......»»
ISPs tell Supreme Court they don’t want to disconnect users accused of piracy
ISPs say Sony's win over Cox would force them to do "mass Internet evictions." Enlarge / The Supreme Court of the United States in Washington, DC, in May 2023. (credit: Getty Images | NurPhoto) Four more large Internet s.....»»
11-Year-Old Arrested After Mass School Shooting Threat: Sheriff
11-Year-Old Arrested After Mass School Shooting Threat: Sheriff.....»»
Freshwater oysters could be key to developing stronger, "greener" adhesives
If you think oysters are just delicious seafood, think again. Freshwater oysters produce an adhesive that may hold the secret to developing more environmentally friendly glues with applications from dental care to construction and shipping. An intern.....»»
A toxic chemical was blamed for killing thousands of Teesside crabs, but a study explains why pyridine isn"t the culprit
In October 2021, thousands of dead and dying crabs and lobsters washed up along 45 miles (70km) of coastline in north-east England. This mass-mortality event coincided with the redevelopment of one of the UK's largest ports at Teesside......»»
An unexpected protein connection in maize growth and defense could enhance crop resilience
Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored......»»
Team discovers naturally occurring DNA-protein hybrids
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»
Widgetsmith updated for iOS 18 with aesthetic new ‘Actions’ system
Widgetsmith, everyone’s favorite aesthetic app, is getting a big update today to take advantage of iOS 18. As detailed in a blog post, Widgetsmith 7 “takes device customization to all-new levels.” The update focuses on new customizable Actions.....»»
Earth"s greatest mass extinction 250 million years ago shows what happens when El Niño gets out of control
Around 252 million years ago, the world suddenly heated up. Over a geologically brief period of tens of thousands of years, 90% of species were wiped out. Even insects, which are rarely touched by such events, suffered catastrophic losses. The Permia.....»»
Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»
The ripple effects of regulatory actions on CISO reporting
In this Help Net Security video, Sara Behar, Content Manager at YL Ventures, discusses how recent regulatory actions and high-profile legal incidents involving cybersecurity leaders have influenced CISO reporting. In a recent report of the CISO Circu.....»»