Genetic base editing treats sickle cell disease in mice
Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This treat.....»»
Can climate change accelerate transmission of malaria? New research sheds light on impacts of temperature
Malaria is a mosquito-borne disease caused by a parasite that spreads from bites of infected female Anopheles mosquitoes. If left untreated in humans, malaria can cause severe symptoms, health complications and even death......»»
Researchers uncover "parallel universe" in tomato genetics
In a paper appearing in Science Advances, Michigan State University researchers have unraveled a surprising genetic mystery centered on sugars found in what gardeners know as "tomato tar.".....»»
Imaging technique shows new details of peptide structures
A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies—stacks of peptides that include amyloid beta, most notably associated with Alzheimer's disease......»»
Researchers unveil PI3K enzyme"s dual accelerator and brake mechanisms
A group of researchers have expanded conventional knowledge on a critical enzyme that controls cell migration. In a publication in the journal Nature Communications, they reported that phosphoinositide 3-kinase (PI3K) not only acts as an accelerator.....»»
Unveiling the mysteries of cell division in embryos with timelapse photography
The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis are well-studied in the so-called somatic cells—the cells that have a specialized function, like skin and muscle cells—they remain elusive in the first cells of.....»»
Vast DNA tree of life for plants revealed by global science team using 1.8 billion letters of genetic code
A new paper published today (April 24) in the journal Nature by an international team of 279 scientists led by the Royal Botanic Gardens, Kew presents the most up-to-date understanding of the flowering plant tree of life......»»
Social change may explain decline in genetic diversity of the Y chromosome at the end of the Neolithic period
The emergence in the Neolithic of patrilineal social systems, in which children are affiliated with their father's lineage, may explain a spectacular decline in the genetic diversity of the Y chromosome observed worldwide between 3,000 and 5,000 year.....»»
Enhanced CRISPR method enables stable insertion of large genes into the DNA of higher plants
Scientists at the Leibniz Institute of Plant Biochemistry (IPB) have succeeded for the first time in stably and precisely inserting large gene segments into the DNA of higher plants very efficiently. To do this, they optimized the gene-editing method.....»»
Fragments of bird flu virus genome found in pasteurized milk, FDA says
The test cannot tell if the virus is live. The FDA still assess milk supply as safe. Enlarge / Cows being milked (credit: Getty | Edwin Remsberg) The Food and Drug Administration on Tuesday announced that genetic fragmen.....»»
Scientists study lipids cell by cell, making new cancer research possible
Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors. Scientists are celebrating a new technique that lets them study the fatty contents of cancer cells, one by one......»»
Best Verizon new customer deals: Galaxy S24, iPhone and more
Are your monthly cell phone bills bleeding you dry? Save some cash with these Verizon new customer deals......»»
Researchers uncover natural variation in wild emmer wheat for broad-spectrum disease resistance
Bread wheat is one of the most important staple crops for millions of people and is apparently the largest cultivated and traded cereal worldwide. Bread wheat is a hexaploid species with three subgenomes (2n = 6x = 42, AABBDD) that has undergone two.....»»
Researchers map protein network dynamics during cell division
An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the.....»»
Scientists find common genes defending coffee plants against devastating disease
Arabica coffee is the most economically important coffee globally and accounts for 60% of coffee products worldwide. But the plants it hails from are vulnerable to a disease that, in the 1800s, devastated Sri Lanka's coffee empire......»»
Saturday Citations: Irrationality modeled; genetic basis for PTSD; Tasmanian devils still endangered
Hello, stakeholders. (This is the nongendered term of address I've been workshopping because I see "folks" in too many social media posts.) Researchers this week reported on an AI model that attempts to emulate human irrationality in decision-making,.....»»
Cities: Skylines 2 team apologizes, makes DLC free and promises a fan summit
A "complete focus on improving the base game" will happen before more paid DLC. Enlarge / Like the Beach Properties DLC itself, this property looks a bit unfinished and in need of some focus. (credit: Paradox Interactive).....»»
Previously unknown details of aphids in flight to contribute to improved crop security
Researchers led by a scientist at Keele University in Staffordshire have studied the previously unknown flight mechanisms of a common crop pest, to learn more about their movements in a bid to improve food security and prevent the spread of disease......»»
Researchers set new standards for nanoparticles, helping patients with MS, ALS, Parkinson"s disease
Is it possible for nanoparticles to go through the digestive system and deliver medicine directly to the brain tissue? Researchers from Michigan State University say yes, and their latest findings are expected to benefit patients with neurodegenerati.....»»
This AI-controlled jet fighter has now flown against human pilots
After flying against simulated opponents, the AI agent has taken on humans. Enlarge / The X-62A VISTA Aircraft flying above Edwards Air Force Base, California. (credit: Kyle Brasier, U.S. Air Force) An AI test pilot has.....»»
RNA"s hidden potential: New study unveils its role in early life and future bioengineering
The beginning of life on Earth and its evolution over billions of years continue to intrigue researchers worldwide. The central dogma or the directional flow of genetic information from a deoxyribose nucleic acid (DNA) template to a ribose nucleic ac.....»»