Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2
ABC transporters constitute a major class of multidrug resistance proteins, e.g., in cancer cells. Membrane lipids have been long known to influence the structure and functional dynamics of these proteins. However, previous structural and biochemical.....»»
Supergene research solves the mystery of tiny ant queens
An ant colony is sustained through complex social dynamics, with each member—the queen, males and workers (sterile females)—contributing to the greater community. Some species add complexity to this dynamic with the addition of rather small queen.....»»
SWAT team’s Spot robot shot multiple times during standoff
It's believed to be the first time Boston Dynamics' dog-like robot has taken a bullet during active duty and highlights how it can make police work safer......»»
Long-period oscillations control the sun"s differential rotation: Study
The sun's differential rotation pattern has puzzled scientists for decades: While the poles rotate with a period of approximately 34 days, mid-latitudes rotate faster and the equatorial region requires only approximately 24 days for a full rotation......»»
Team modulates electronic state of single-atom catalysts by CO molecular decoration for efficient methane conversion
Direct methane conversion has advantages such as low energy consumption, fewer processes, and better economics. However, it is difficult to activate methane at room temperature due to the high dissociation energy of C-H bonds of methane. Additionally.....»»
You may be offered a free premium Telegram subscription – but please don’t accept
On the face of it, getting a free premium Telegram subscription direct from the company seems like a pretty sweet deal, giving you access to features like transcribing voice messages into texts. But the price of this particular free deal is way too h.....»»
Seeing this eclipse is probably the highest-reward, lowest-effort thing one can do in life
Don't not see it. Enlarge / The path of totality for the April 8 eclipse. (credit: National Solar Observatory) If you enter "how to see the eclipse" into your favorite search engine, you're bound to see thousands—milli.....»»
Baldur’s Gate 3 isn’t getting DLC or a sequel from Larian, and that’s OK
Games like Baldur's Gate 3 and The Legend of Zelda: Tears of the Kingdom aren't getting expansions or direct sequels anytime soon, but I'm content with that......»»
Exploring China"s water usage trends and sustainability
Against the backdrop of growing global concern over water scarcity, China, has been grappling with the complexities of water dynamics and their impact on economic growth and environmental protection. A study published in the journal Advances in Water.....»»
Scientists explore complex pattern of tipping points in the Atlantic"s current system
An international team of scientists has warned against relying on nature providing straightforward 'early warning' indicators of a climate disaster, as new mathematical modeling shows new fascinating aspects of the complexity of the dynamics of clima.....»»
Breakthrough in light manipulation: Unveiling novel finite barrier bound states
Exploring wave propagation and localization in various media has been a core focus in optics and acoustics. Specifically, in photonics and phononics, scientists have been dedicated to understanding and controlling the behavior of light and sound wave.....»»
How to get Meowmere in Stardew Valley
The Meowmere is a secret weapon in Stardew Valley that is a direct reference to Terraria. It's very well-hidden, so follow our steps to get your hands on it......»»
Scientists elucidate the role of GlyT1 in anti-schizophrenia drugs
Schizophrenia is a highly disabling mental disorder, and numerous studies have shown that the hypofunction of the N-methyl-d-aspartate (NMDA) receptor is one of its pathogenic mechanisms. Glycine transporter 1 (GlyT1), a glycine transporter protein,.....»»
Genesis brand names Troy Saito to direct U.S sales and operations
Saito will oversee all U.S sales and retail operations and focus on strategy and retailer operations. He will be working closely with all 239 domestic dealerships, Genesis said......»»
Intel receives $8.5 billion from US for expanding high-end fab capacity
Chips Act funding will primarily be directed toward development of Intel’s 18A node. Enlarge (credit: Bloomberg) Intel will receive $8.5 billion in direct funding and $11 billion in loans from the US government to expa.....»»
Researchers explore how beluga whale melon changes shape during social interaction
A trio of animal science researchers at the University of Rhode Island, in the U.S., has identified five major shapes displayed by the beluga whale melon. For their study published in the journal Animal Cognition, Justin Richard, Isabelle Pellegrini,.....»»
1% of users are responsible for 88% of data loss events
Data loss is a problem stemming from the interaction between humans and machines, and ‘careless users’ are much more likely to cause those incidents than compromised or misconfigured systems, according to Proofpoint. While organizations a.....»»
Monitoring and measuring biodiversity requires more than just numbers: Scientists advocate for change
Assessing wildlife populations, as well as understanding the dynamics of their numbers and distributions across various regions, is a critical measure known in science as abundance......»»
Research team establishes synthetic dimension dynamics to manipulate light
In the realm of physics, synthetic dimensions (SDs) have emerged as one of the frontiers of active research, offering a pathway to explore phenomena in higher-dimensional spaces, beyond our conventional 3D geometrical space. The concept has garnered.....»»
Direct laser writing on halide perovskites: From mechanisms to applications
Metal halide perovskites have become well-deserved "star" materials among a variety of semiconductors owing to their excellent optoelectronic properties, such as high photoluminescence (PL) quantum yield (QY), high absorption coefficient, tunable ban.....»»
Conduction of catalytic properties from buried transitional metals to exposed inert main group metals
The electronic interaction between buried single transitional metal and adjacent aluminum atoms via metallic bonding can be well demonstrated......»»