Deciphering the molecular dynamics of complex proteins
Which structures do complex proteins adopt in solution? Konstanz biophysicists answer this question using the example of ubiquitin dimers as well as a new combination of high-resolution NMR spectroscopy and sophisticated computer simulations......»»
Chemists discover new ways in which single-celled organisms organize their DNA
It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden Ph.D. candidate Samuel Schwab has found that the histones in these organisms are much more diverse.....»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Researchers achieve aluminum molecular ring-based rotaxane and polyrotaxane
Rotaxanes have garnered interest for their unique structures consisting of mechanically interlocked axles and macrocycles. Numerous organic macrocycles have been employed to construct rotaxanes, including crown ether, cyclobis(paraquat-p-phenylene),.....»»
Research proposes theory to model interplay of personal and social beliefs
The beliefs we hold develop from a complex dance between our internal and external lives. Our personal-level cognition and our relationships with others work in concert to shape our views of the world and influence how likely we are to update those v.....»»
Opnova emerges from stealth with $3.75 million in funding
Opnova announced its official launch, introducing an agentic AI platform designed to close the automation gap in complex operational workflows. Backed by $3.75 million in pre-seed funding co-led by Faber, ScaleX, and Preface Ventures, Opnova is set t.....»»
Researchers explore physiological and molecular processes underlying graft healing
Grafting has long been a cornerstone in agriculture and forestry, allowing for the propagation of desirable plant traits and improved resistance to environmental challenges. Despite its widespread application, grafting still encounters obstacles, inc.....»»
Light-induced immunoassay can selectively detect coronavirus spike proteins in five minutes
Like moths to a flame, microbes can also be moved by light. Using this knowledge, researchers from Osaka Metropolitan University's Research Institute for Light-induced Acceleration System (RILACS) have demonstrated a method to detect the presence of.....»»
Forescout for OT Security secures OT, IoT, and IT hybrid environments
Forescout announced its new SaaS Operational Technologies (OT) solution. Forescout for OT Security is a security solution that allows organizations to secure complex, heterogeneous OT, IoT/IoMT, and IT environments whether they are fully in cloud, co.....»»
Reducing floodplain development doesn"t need to be complex, say researchers
A paper, titled "How local governments avoid floodplain development through consistent implementation of routine municipal ordinances, plans, and programs," published in Oxford Open Climate Change uncovers evidence suggesting that, contrary to expect.....»»
Bioengineers create new substrate to study wood-decomposing enzyme
Researchers want to transform the natural and abundant resource wood into useful materials, and central to that is a molecular machine found in fungi that decomposes the complex raw material into its basic components......»»
Greenhouse gains: Cucumbers genetic upgrade through innovative pollen tech
Genetic modification in horticultural crops, particularly within the Cucurbitaceae family, is often hindered by complex tissue culture requirements and environmental pressures such as climate change. Traditional transformation techniques, like Agroba.....»»
DNA origami and fluorescent probes can precisely release molecular cargo
In the world of nanotechnology, the development of dynamic systems that respond to molecular signals is becoming increasingly important. The DNA origami technique, whereby DNA is programmed so as to produce functional nanostructures, plays a key role.....»»
Scientists find new epigenetic switch, revealing how genes are regulated in early development
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early emb.....»»
Ocean waves grow way beyond known limits, new research finds
Scientists have discovered that ocean waves may become far more extreme and complex than previously imagined......»»
Zirconium metals under extreme conditions found to deform in surprisingly complex ways
Materials are crucial to modern technology, especially those used in extreme environments like nuclear energy systems and military applications. These materials need to withstand intense pressure, temperature and corrosion. Understanding their lattic.....»»
Computational tool can pinpoint causal relationships from complex biological data
Researchers have developed a tool that provides new insights into cause-and-effect relationships between cells and how these change over time......»»