Computer simulations of proteins help unravel why chemotherapy resistance occurs
Understanding why and how chemotherapy resistance occurs is a major step toward optimizing treatments for cancer. A team of scientists including Markus Seeliger, Ph.D., of the Stony Brook Cancer Center and Renaissance School of Medicine at Stony Broo.....»»
Is Betelgeuse actually a binary star?
Betelgeuse has been a favorite among amateur astronomers for many years. However you pronounce it, its unexpected dimming draws even more attention to this red supergiant variable star in Orion. It has a few cycles of variability. One of them occurs.....»»
Supercomputer simulations reveal the nature of turbulence in black hole accretion disks
Researchers at Tohoku University and Utsunomiya University have made a breakthrough in understanding the complex nature of turbulence in structures called accretion disks surrounding black holes, using state-of-the-art supercomputers to conduct the h.....»»
Study finds flexibility and helical twists of actin filaments regulate actin-binding proteins
Researchers at Kanazawa University have published an article in eLife deciphering the actin structure-dependent preferential cooperative binding of cofilin......»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Moths may use disco gene to regulate day/night cycles
How does one species become two? If you're a biologist, that's a loaded question. The consensus is that, in most cases, the process of speciation occurs when individuals from a single population become geographically isolated. If they remain separate.....»»
There’s a scary new way to undo Windows security patches
A security researcher has released a new tool that can unpatch your Windows computer and expose it to old vulnerabilities......»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Using machine learning to speed up simulations of irregularly shaped particles
Simulating particles is a relatively simple task when those particles are spherical. In the real world, however, most particles are not perfect spheres, but take on irregular and varying shapes and sizes. Simulating these particles becomes a much mor.....»»
3D shapes of viral proteins point to previously unknown roles
Viruses are tricky to keep up with. They evolve quickly and regularly develop new proteins that help them infect their hosts. These rapid shifts mean that researchers are still trying to understand a multitude of viral proteins and precisely how they.....»»
Struggling to Unlock Your Phone? You Might Have Lost Your Fingerprints
The absence of these identifying marks—which can be the result of excessive typing, manual work, chemotherapy, or sports—is becoming more of an issue in the age of biometrics......»»
Simulations identify how critical elements distribute in abundant mineral ores
Nickel (Ni) and cobalt (Co) are critical elements for modern technologies, with high-grade Ni and Co ores becoming increasingly scarce. Mafic and ultramafic deposits are low-grade, abundant alternatives to traditional Ni and Co ores. However, new met.....»»
Tomato ripening study highlights cell wall component interactions
Tomato fruit ripening involves intricate biochemical and structural changes, particularly within the cell wall, which are vital for the fruit's final texture and quality. These changes include modifications in polysaccharides and proteins, but the sp.....»»
The Quantum Mechanics of the Greenhouse Effect
Carbon dioxide’s powerful heat-trapping effect has been traced to a quirk of its quantum structure. The finding may explain climate change better than any computer model......»»
Ecosystems study finds the higher the environmental stress, the lower the resistance to global change
An international study led by the Institute of Natural Resources and Agrobiology of Seville (IRNAS-CSIC), of the Spanish National Research Council (CISC), has shown that as the number of global change factors increases, terrestrial ecosystems become.....»»
Vision Pro will live or die on Apple’s own words: ‘spatial computer’
Apple’s Vision Pro has been available for over half a year. Despite an initial wave of excitement and viral buzz around its launch, these days Vision Pro discourse isn’t very positive. The device’s rumored sales struggles are often highlighted,.....»»
HBADA E3 Ergonomic Office Chair: Your waist is going to thank you!
If you’re someone who works in front of a computer often, chances are you’re also spending a lot of time sitting down. There have been numerous studies showing that sitting for an extended period of time can be detrimental to your health in the l.....»»
Apple-1 owned by Apple"s first applications engineer sells for over $300,000
An Apple-1 computer owned by Apple's first applications engineer, Dana Redington, has commanded quite the price on the auction block, along with a panoply of other Apple-related items.Image Credit: RR AuctionsIn 1978, a pile of soon-to-be-discarded h.....»»
Journalists and social media users are key drivers behind product recall decisions, says researcher
Canada saw a record 2,330 product recalls in 2023—more than six per day and the highest since the federal government started releasing the data in 2011. A product recall occurs when a manufacturer takes action to remove consumer goods with safety d.....»»
Burglars trash Toyota showroom
The vandals, whom managers identified as an employee and a friend they had recently fired, destroyed 60 computer monitors and five TVs in a half hour......»»
Novel carbon nanohorn-based treatment enables efficient delivery of drugs in cancer therapy
Cancer remains one of the most challenging diseases to treat due to its complexity and tendency to metastasize (spread into, or invade, nearby tissues or distant places in the body to form new tumors). Traditional therapies, such as chemotherapy and.....»»