Computer simulations of proteins help unravel why chemotherapy resistance occurs
Understanding why and how chemotherapy resistance occurs is a major step toward optimizing treatments for cancer. A team of scientists including Markus Seeliger, Ph.D., of the Stony Brook Cancer Center and Renaissance School of Medicine at Stony Broo.....»»
Apple released the iMac 26 years ago and it"s better than ever
Even if every part of the iMac has radically evolved, it's still the only computer that debuted in 1998 that you can buy in 2022, because Apple got its core purpose right on this day, 26 years ago, when it went on saleIf there's a single Mac that is.....»»
Could manure and compost act like probiotics, reducing antibiotic resistance in urban soils?
Urban soils often contain chemical contaminants, such as heavy metals or trace amounts of antibiotics, along with higher levels of antibiotic-resistant bacteria. New research from the University of Maryland suggests that, in some cases, boosting urba.....»»
New tools for fungicide resistance detection
Researchers at the Center for Crop and Disease Management (CCDM) have developed a new method for detecting fungicide resistance, enabling them to detect multiple mutations, both known and novel, in just one test......»»
New insights into neural circuit imaging: A comparison of one-photon and two-photon techniques
In the quest to unravel the complexities of neural circuits, scientists are beginning to use genetically encoded voltage indicators (GEVIs) to visualize electrical activity in the brain. These indicators are crucial for understanding how neurons comm.....»»
Light-responsive gene regulation at the mRNA level
Researchers at the University of Bayreuth have established a new optogenetic approach that can control the bacterial production of proteins at the mRNA level using blue light. The new system gates the activation of the genetic substance particularly.....»»
NIST releases finalized post-quantum encryption standards
NIST has finalized its principal set of encryption algorithms designed to withstand cyberattacks from a quantum computer. The announced algorithms are specified in the first completed standards from NIST’s post-quantum cryptography (PQC) standardiz.....»»
A water tracer tool to understand the role of lateral flow in hydrologic simulations
Lateral water movement from ridges to valleys plays a key role in organizing water and energy at the watershed scale. But it has long been neglected in traditional land models......»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
Rewriting the evolutionary history of critical components of the nervous system
A new study has rewritten the conventionally understood evolutionary history of certain proteins critical for electrical signaling in the nervous system......»»
Photolithography research shows computer chips have the potential to become even smaller
Researchers at the Paul Scherrer Institute PSI have been improving the resolution of a process known as photolithography. They hope to use their technique to help advance the miniaturization of computer chips......»»
New model framework aims to predict postfire debris flow behavior before a fire occurs
New research from a team at Los Alamos National Laboratory is improving landslide prediction capabilities, making simulations faster and more accurate, which in turn will improve safety for communities that are at risk of their infrastructure being w.....»»
Researchers identify body"s "quality control" regulator for protein folding, could lead to targeted treatments
Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
This 1TB Mac Studio is discounted to $1,999, plus get 3 years of AppleCare for $139
Apple's current Mac Studio desktop computer with an upgrade to 1TB of storage is marked down to $1,999 thanks to an exclusive coupon discount. Plus, grab bonus savings on AppleCare.Pick up a 1TB Mac Studio for $1,999.The $200 savings* can be unlocked.....»»
Redefining the computer whiz: Research shows diverse skills valued by youth
New study reveals diverse perceptions of the "ideal" computer science student among young people......»»
Almost unfixable “Sinkclose” bug affects hundreds of millions of AMD chips
Worse-case scenario: "You basically have to throw your computer away." Security flaws in your computer's firmware, the deep-seated code that loads first when you turn the machine on and controls even how its operating system boots up.....»»
Someone has found a way to fix software bricked HomePods
Unlike the HomePod mini, both the original HomePod and the HomePod 2 don’t have a USB cable, which means there’s no easy way to connect them to a computer to fix software issues. And unfortunately, there are a lot of users who have had their Home.....»»
How to download Microsoft Word
Want to start creating documents like articles, essays, and reports? Here’s how to download Microsoft Word on your computer and mobile device......»»
Researchers develop AI model that predicts the accuracy of protein–DNA binding
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the t.....»»
Biocides are a useful tool to combat antibiotic resistance but appropriate use is vital, scientists suggest
A recent review in the journal Sustainable Microbiology discusses how the use of biocides can promote well-being—but must only be used when there are clear benefits......»»