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Biologists sequence proteins by pulling them through nanopores

A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»

Category: topSource:  theglobeandmail18 hr. 43 min. ago

Unraveling the DNA mystique of Saposhnikovia divaricata: New horizons in herbal medicine

Scientists have decoded the genetic blueprint of Saposhnikovia divaricata, a traditional medicinal herb. Their research provides a detailed genome sequence, shedding light on the plant's evolutionary adaptations and the genetic foundations of its the.....»»

Category: topSource:  physorgRelated NewsJul 17th, 2024

Study finds persistent proteins may influence metabolomics results

Van Andel Institute scientists have identified more than 1,000 previously undetected proteins in common metabolite samples, which persist despite extraction methods designed to weed them out......»»

Category: topSource:  physorgRelated NewsJul 17th, 2024

Study of colorful crayfish challenges theories of bright coloration as adapted phenotype

A pair of biologists, one with West Liberty University, the other with Arizona State University, both in the U.S., has found evidence that challenges theories surrounding bright coloration always functioning as an adapted phenotype......»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

Evolutionary biologists investigate how plant cold specialists can adapt to the environment

Plant cold specialists like the spoonworts have adapted well to the cold climates of the Ice Ages. As cold and warm periods alternated, they developed a number of species that also resulted in a proliferation of the genome......»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

Biologists determine the liver is the source of free glycans in the bloodstream

In a rat study, RIKEN biologists have solved the mystery of where glycan molecules in the blood come from, tracking them down to the liver. This finding could lead to new biomarkers for liver-related diseases......»»

Category: topSource:  physorgRelated NewsJul 11th, 2024

Does the Samsung Galaxy Z Fold 6 have a headphone jack?

The Galaxy Z Fold 6 is officially out, but before pulling the trigger, you might be wondering if it has a headphone jack. Here's the scoop......»»

Category: topSource:  digitaltrendsRelated NewsJul 10th, 2024

AI-powered atlas reveals how proteins behave inside cells

Scientists at the University of Cambridge have developed an atlas of proteins describing how the proteins behave inside human cells. This tool could be used to search for the origins of diseases related to proteins misbehaving, such as dementia and m.....»»

Category: topSource:  physorgRelated NewsJul 10th, 2024

Egg cell maintenance: Long-lived proteins may be essential for fertility

Female mammals—including humans—are born with all of their egg cells. Of a woman's one to two million egg cells, about 400 mature before menopause and can be fertilized. Some egg cells therefore survive for several decades—and need to remain fu.....»»

Category: topSource:  physorgRelated NewsJul 9th, 2024

Restored oyster sanctuaries host more marine life despite parasites, biologists discover

In the campaign to restore Chesapeake Bay, oyster sanctuaries rank among the most hotly contested strategies. But new research suggests these no-harvest areas are working, and not only for the oysters......»»

Category: topSource:  theglobeandmailRelated NewsJul 8th, 2024

Novel strategy proposed for selectively targeting G-quadruplex at specific genome loci

DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many cases their causative effects are largely unclear.....»»

Category: topSource:  physorgRelated NewsJul 8th, 2024

AI approach optimizes development of antibody drugs

Proteins have evolved to excel at everything from contracting muscles to digesting food to recognizing viruses. To engineer better proteins, including antibodies, scientists often iteratively mutate the amino acids—the units that are arranged in a.....»»

Category: topSource:  physorgRelated NewsJul 5th, 2024

The influence of peptoid sequence on the mechanisms and kinetics of 2D assembly

Two-dimensional (2D) materials have unique physical and chemical properties and potential for a wide variety of applications. Peptoids, a type of molecule, compose a class of sequence-defined polymers that mimic biological compounds and can self-asse.....»»

Category: topSource:  pcmagRelated NewsJul 4th, 2024

Energy landscape theory sheds light on evolution of foldable proteins

A new study led by Rice University's Peter Wolynes offers new insights into the evolution of foldable proteins. The research was published in the Proceedings of the National Academy of Sciences......»»

Category: topSource:  physorgRelated NewsJul 4th, 2024

New mRNA technology turns cells into long-lasting drug factories

A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body,.....»»

Category: topSource:  physorgRelated NewsJul 3rd, 2024

Mutations in a non-coding gene associated with intellectual disability

A gene that only makes an RNA is linked to neurodevelopmental problems. Enlarge / The spliceosome is a large complex of proteins and RNAs. (credit: NCBI) Almost 1,500 genes have been implicated in intellectual disabiliti.....»»

Category: topSource:  arstechnicaRelated NewsMay 31st, 2024

Researchers uncover protein SRSF1"s uncommon ability to bind and unfold RNA G-quadruplexes

RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department of Chemistry Professor Jun Zhang, Ph.D., and his te.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

Q&A: How to make sustainable products faster with artificial intelligence and automation

By modifying the genomes of plants and microorganisms, synthetic biologists can design biological systems that meet a specification, such as producing valuable chemical compounds, making bacteria sensitive to light, or programming bacterial cells to.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

Novel method for mass production of recombinant proteins uses mono-sodium glutamate

Mass production of recombinant proteins using yeast cell "factories" needs methanol, a compound that requires safe handling, carries the risk of catching fire, and sometimes produces harmful byproducts. Researchers at the Department of Biochemistry (.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

Chemists, biologists, archaeologists: Who will unearth the recipes of our ancestors?

Using a new multidisciplinary approach, a team from UNIGE and CNRS has retraced the food practices of a Senegalese village. This method will be useful for other archaeological research......»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

Understanding how zwitterionic polymers can lead to safer drugs and disease prevention

Proteins are vital biomolecules responsible for performing various functions in the human body and are thus regarded as the workhorses of a cell. The primary structure of a protein is composed of different amino acids coming together. The structure s.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024