Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
A systematic review of three key sugar metabolism proteins: HXK, SnRK1 and TOR
Sugar signaling is one of the most important regulatory signals for plant growth and development, and its metabolic network contains many regulatory factors. Sugar signaling molecules regulate cellular activities and organismal development by interac.....»»
A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»
How to delete a Discord server on desktop and mobile
Need a break from Discord? We know the feeling. Fortunately, pulling down your server isn’t too difficult. Here’s a guide to help......»»
How evolution has optimized the magnetic sensor in birds
Migratory birds are able to navigate and orientate with astonishing accuracy using various mechanisms, including a magnetic compass. A team led by biologists Dr. Corinna Langebrake and Prof. Dr. Miriam Liedvogel from the University of Oldenburg and t.....»»
Evolutionary biologists show that the color variants of female cuckoos are based on ancient mutations
Every cuckoo is an adopted child—raised by foster parents, into whose nest the cuckoo mother smuggled her egg. The cuckoo mother is aided in this subterfuge by her resemblance to a bird of prey. There are two variants of female cuckoos: a gray morp.....»»
Researchers create artificial cells that act like living cells
In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that look and act like cells f.....»»
Supercomputer simulation reveals new mechanism for membrane fusion
An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse......»»
Researchers report on mechanisms of gene regulatory divergence between species
Closely related animal species can look physically different, but you might be surprised to learn that those differences can result not only from DNA sequence changes that alter proteins' structure or function, but also because changes in the DNA aff.....»»
Researchers map protein network dynamics during cell division
An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the.....»»
In Ecuadoran Amazon, butterflies provide a gauge of climate change
Biologists on a trail in the Ecuadoran Amazon hold their breath as they distribute a foul-smelling delicacy to lure butterflies, critical pollinators increasingly threatened by climate change......»»
Uncovering key players in gene silencing: Insights into plant growth and human diseases
Monash University biologists have shed light on the intricate molecular mechanisms that are responsible for gene silencing induced by expanded repeats in an international study published today in Nature Plants......»»
Light show in living cells: New method allows simultaneous fluorescent labeling of many proteins
Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge—especially in living cells, as the required fluorescent labeling had to be individually attached to each p.....»»
How a calcium-sensing protein multitasks
The calcium-sensing receptor is critical for maintaining healthy calcium levels, but CaSR is also well-known for its side hustles. The receptor is increasingly recognized for its ability to detect other ions and proteins and for its role in breast ca.....»»
Arboviruses, mosquitoes and potential hosts tracked in real time in São Paulo city
The technology used to sequence SARS-CoV-2 at record speed early in the COVID-19 pandemic has been successfully tested as a technique to monitor arboviruses and diseases transmitted mainly by mosquitoes......»»
If you have to watch one Netflix show this April, stream this one
A series celebrating its tenth anniversary is pulling into port at Netflix this week, and if you have to watch one Netflix show in April, stream this one......»»
New study calls into question prior study results that found tumor transmission slowing in Tasmanian devils
A trio of biologists and veterinarians with CRG Barcelona, the University of Cambridge and The Barcelona Institute of Science and Technology, respectively, has found evidence contradicting results found by a prior team of researchers who claimed that.....»»
Discovery of bacterial proteins that induce asexual reproduction in insects
From microbes in the human gut to symbiotic algae in coral reefs, research in recent decades has increasingly revealed the pivotal roles that microorganisms (or microbial species) play in shaping the biology of host organisms and of broader ecosystem.....»»
Nanovials method for immune cell screening uncovers receptors that target prostate cancer
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor proteins found on their sur.....»»
Decoding the language of cells: Profiling the proteins behind cellular organelle communication
In cellular biology, unraveling the complexities of cellular function at the molecular level remains a paramount endeavor. Significant scientific focus has been placed on understanding the interactions at organelle contact sites, especially between m.....»»
Biologists reveal how gyrase resolves DNA entanglements
Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in every cell in the body have one thing in common; th.....»»